The CHIME database is the largest longitudinal physiologic dataset of infants. Between May 1994 and February 1998, 1079 infants were enrolled in the following study groups: healthy term (n=306), preterm infants <1750g without significant morbidity (n=443), sibling of SIDS (n=178), and babies experiencing apparent life-threatening events (n=152).
The objectives of the study were to: determine whether home apnea monitors employing event recordings were effective in identifying episodes that are dangerous to the infant's health; determine the conditions that optimize the use of apnea monitors in high risk infants; correlate physiological markers, health status, and behavior with the propensity for life-threatening events; and provide important information on the maturation of heart and respiratory function in sleeping infants.
The database contains raw and analyzed physiologic waveforms from overnight polysomnogram recordings and the home monitor recordings:
Data collected by CHIME also include sociodemographic and medical information on the mother and infant at entry and from scheduled medical follow-up visits through 1-year of age, weekly phone calls, monitor knowledge and satisfaction scales, periodic assessments with the Bayley II, NCAST, subscales of the Parenting Stress Index, and hospitalizations.
Funded by NICHD grant# 2U10HD2906709A1.
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Last updated: January 29, 2004.